Genotoxicity Evaluation of Commercially Available Acid Red Dye by Comet Assay in Fish (Cyprinus carpio)

Autores/as

  • Venkataramulu Deepa International Institute of Biotechnology and Toxicology, Padappai, India
  • T. N. Sathya International Institute of Biotechnology and Toxicology, Padappai, India
  • P. Balakrishna Murthy International Institute of Biotechnology and Toxicology, Padappai, India
  • P. Neelakanta Reddy Bio-organic Chemistry Laboratory, Central Leather Research Institute, Chennai, India

DOI:

https://doi.org/10.5132/jbse.2011.01.011

Palabras clave:

acid red, commercial dyes, genotoxicity, comet assay

Resumen

Genotoxicity of commercially available acid red dye on fish was evaluated. Fish were exposed to various concentrations of the dye and gill processed for comet assay. Nucleoids were visually scored and categorized into various damage degrees. Significant increase (p < 0.05) in the percentage and distribution of damaged nucleoids was recorded in all dye-treated groups over control. DNA damage scores (AU) increased with exposure concentrations and dose-response was observed at higher doses. From the results it is concluded that commercially available acid red dye is potentially genotoxic to fish. The results are preliminary and further studies are warranted to acknowledge this effect.

Descargas

Publicado

2011-12-04

Cómo citar

Deepa, V., Sathya, T. N., Murthy, P. B., & Reddy, P. N. (2011). Genotoxicity Evaluation of Commercially Available Acid Red Dye by Comet Assay in Fish (Cyprinus carpio). Ecotoxicology and Environmental Contamination, 6(1), 69–72. https://doi.org/10.5132/jbse.2011.01.011

Número

Vol. 6 Núm. 1 (2011)

Sección

Original Articles

Licencia

Derechos de autor 2012 Ecotoxicology and Environmental Contamination

Creative Commons License

Esta obra está bajo una licencia internacional Creative Commons Atribución 4.0.

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